Your liver doesn’t age like the rest of your body. At this point it will be about 3 years old

Deepak Gupta June 3, 2022
Updated 2022/06/03 at 10:15 PM

This is probably not an issue you’ve ever debated, as it just seems like a natural process. However, know that regardless of her age, her liver stopped aging in the three years.

After all, we all actually have an inner child.

According to new research, the human liver remains quite young while the rest of the body ages. So regardless of your age - whether you're 18, 40, or 60 - know that your liver could be less than three years old (according to the average found).

It is one of the largest and most important organs in the human body and its main function is, in a simple way, to eliminate toxins. Because of this role, he is constantly in contact with harmful substances and, therefore, has a high probability of being injured. To prevent this from happening, it is an organ that, unlike the rest, has the ability to regenerate itself after suffering damage.

Research that reveals that the liver stops aging at age three was published in Cell Systems.

A young liver for life

One team of biologists, physicists, mathematicians and clinicians analyzed the liver of a range of individuals aged between 20 and 84 years. To the group's surprise, the liver cells from the cadavers were roughly the same age.

Some studies have pointed to the possibility that liver cells are long-lived while others have shown constant rotation. It became clear to us that if we want to know what happens in humans, we need to find a way to directly assess the age of human liver cells.

Revealed Olaf Bergmann, molecular biologist and leader of the research group at the Center for Regenerative Therapies Dresden (CRTD) of Technische Universität Dresden.

The researchers found that "it doesn't matter if you're 20 or 84, your liver remains, on average, just under three years old."

It is not easy to determine the age of cells

Despite all the knowledge that currently exists, determining the biological age of human cells is still a challenge, as the techniques that are used in animals cannot be used in humans. So the team used mathematical modeling and a technique called retrospective birth dating. The latter dates human cells based on the levels of a carbon isotope that spread through the atmosphere after conducting nuclear tests in the mid-20th century.

In this way, the team realized that liver turnover is not affected by aging, and realized that the "adjustment of liver mass to the body's needs is strictly regulated through the constant replacement of liver cells". This substitution is an essential process, for example, to control the formation of cancers.

Most of our cells have two sets of chromosomes, but some of them accumulate more DNA as they age. In the end, such cells can carry four, eight, or even more sets of chromosomes.

explained Bergmann.

Olaf Bergmann, molecular biologist and research group leader at the Center for Regenerative Therapies Dresden (CRTD) at the Technische Universität Dresden.

Olaf Bergmann, molecular biologist and research group leader at the Center for Regenerative Therapies Dresden (CRTD) at Technische Universität Dresden

In addition to the liver, the team is still studying the mechanisms that control the regeneration of other tissues, such as the brain and heart.

Our research shows that studying cell turnover directly in humans is technically very challenging, but can provide unparalleled insights into the cellular and molecular mechanisms underlying the regeneration of human organs.

Revealed the leader of the Bergmann investigation group.

In fact, understanding the methods that would allow the regeneration of some of the most important tissues in the human body could be an unprecedented discovery.

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